GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Serpine2 | increases expression | EXP | | 6480464 | CTD | Benzo(a)pyrene results in increased expression of SERPINE2 mRNA | PMID:22228805 PMID:22610609 | Serpine2 | affects methylation | ISO | SERPINE2 (Homo sapiens) | 6480464 | CTD | Benzo(a)pyrene affects the methylation of SERPINE2 promoter | PMID:30157460 | Serpine2 | decreases methylation | ISO | SERPINE2 (Homo sapiens) | 6480464 | CTD | Benzo(a)pyrene results in decreased methylation of SERPINE2 promoter | PMID:27901495 | Serpine2 | increases expression | ISO | SERPINE2 (Homo sapiens) | 6480464 | CTD | Benzo(a)pyrene results in increased expression of SERPINE2 mRNA | PMID:20106945 PMID:21632981 PMID:22316170 PMID:32234424 | Serpine2 | increases methylation | ISO | SERPINE2 (Homo sapiens) | 6480464 | CTD | Benzo(a)pyrene results in increased methylation of SERPINE2 5' UTR | PMID:27901495 | |
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