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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 70069
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cxcl2
Name: C-X-C motif chemokine ligand 2
Acc ID: CHEBI:46677
Term: amphibole asbestos
Definition: A class of asbestos minerals that includes silicates of magnesium, iron, calcium, and sodium.
Chemical ID: MESH:D017636
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cxcl2increases expressionEXP 6480464CTDAsbestos, Amphibole results in increased expression of CXCL2; Asbestos, Amphibole results in increased expression of CXCL2 mRNAPMID:21605006 PMID:27083413
Cxcl2multiple interactionsEXP 6480464CTDDeferoxamine promotes the reaction [Asbestos, Amphibole results in increased expression of CXCL2]; ferric chloride inhibits the reaction [Asbestos, Amphibole results in increased expression of CXCL2]PMID:21605006
Cxcl2increases expressionISOCXCL2 (Homo sapiens)6480464CTDAsbestos, Amphibole results in increased expression of CXCL2 mRNAPMID:20831825
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