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GENE - TERM ANNOTATION REPORT

RGD ID: 69651
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Tgfbr2
Name: transforming growth factor, beta receptor 2
Acc ID: GO:0007179
Term: transforming growth factor beta receptor signaling pathway
Definition: The series of molecular signals initiated by an extracellular ligand binding to a transforming growth factor beta receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
Definition Source(s): GOC:BHF, GOC:mah, GOC:signaling
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tgfbr2 IMP 2302517RGD  
Tgfbr2acts_upstream_of_or_withinISOTgfbr2 (Mus musculus)1624291RGDMGI:2384513 MGI:4949016 PMID:21420963

MGI:4949016 PMID:21420963
Tgfbr2involved_inISOTGFBR2 (Homo sapiens)1624291RGD PMID:12015308 PMID:1333888 PMID:18453574 PMID:24606633 PMID:28131417 PMID:9311995

PMID:12015308 PMID:1333888 PMID:18453574 PMID:24606633 PMID:28131417 PMID:9311995
Tgfbr2involved_inISOTGFBR2 (Homo sapiens) or UniProtKB:P37173-1 or UniProtKB:P37173-21624291RGD PMID:11157754

PMID:11157754
Tgfbr2 TAS 727411RGD  
Tgfbr2involved_inIEAUniProtKB:P37173 or ensembl:ENSP000002957541600115EnsemblGO_REF:0000107

GO_REF:0000107
Tgfbr2involved_inIEAUniProtKB:Q62312 or ensembl:ENSMUSP000000623331600115EnsemblGO_REF:0000107

GO_REF:0000107
Tgfbr2involved_inIBAMGI:98729 or PANTHER:PTN000583678 or Tgfbr2 (Rattus norvegicus) or UniProtKB:P371731600115GO_CentralGO_REF:0000033

GO_REF:0000033
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