GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Srebf1 | multiple interactions | EXP | | 6480464 | CTD | 1,4-bis(2-(3,5-dichloropyridyloxy))benzene inhibits the reaction [[Progesterone co-treated with Estradiol] results in increased expression of SREBF1 mRNA]; [Progesterone co-treated with Estradiol] results in increased expression of SREBF1 mRNA | PMID:21768169 | Srebf1 | decreases expression | ISO | Srebf1 (Rattus norvegicus) | 6480464 | CTD | Estradiol results in decreased expression of SREBF1 mRNA; Estradiol results in decreased expression of SREBF1 protein | PMID:26164745 PMID:32145629 | Srebf1 | decreases expression | ISO | SREBF1 (Homo sapiens) | 6480464 | CTD | Estradiol results in decreased expression of SREBF1 mRNA | PMID:31614463 | Srebf1 | multiple interactions | ISO | SREBF1 (Homo sapiens) | 6480464 | CTD | [Progesterone co-treated with Estradiol] inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in decreased expression of SREBF1 mRNA]; [Progesterone co-treated with Estradiol] inhibits the reaction [Phenobarbital results in decreased expression of SREBF1 mRNA]; Benzo(a)pyrene inhibits the reaction [Estradiol inhibits the reaction [Oleic Acid results in increased expression of SREBF1 mRNA]]; Benzo(a)pyrene inhibits the reaction [Estradiol inhibits the reaction [Oleic Acid results in increased expression of SREBF1 protein]]; Estradiol inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in decreased expression of SREBF1 mRNA]; Estradiol inhibits the reaction [Oleic Acid results in increased expression of SREBF1 mRNA]; Estradiol inhibits the reaction [Oleic Acid results in increased expression of SREBF1 protein]; Estradiol inhibits the reaction [Phenobarbital results in decreased expression of SREBF1 mRNA]; NR1I3 mutant form inhibits the reaction [Estradiol inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in decreased expression of SREBF1 mRNA]]; NR1I3 mutant form inhibits the reaction [Estradiol inhibits the reaction [Phenobarbital results in decreased expression of SREBF1 mRNA]] | PMID:21768169 PMID:31730885 | |
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