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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69454
Species: Mus musculus
RGD Object: Gene
Symbol: Lcn2
Name: lipocalin 2
Acc ID: CHEBI:30563
Term: silicon dioxide
Definition: A silicon oxide made up of linear triatomic molecules in which a silicon atom is covalently bonded to two oxygens.
Chemical ID: MESH:D012822
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Lcn2increases expressionEXP 6480464CTDSilicon Dioxide results in increased expression of LCN2 mRNA; Silicon Dioxide results in increased expression of LCN2 proteinPMID:23221170 PMID:26345256 PMID:29341224
Lcn2decreases expressionISOLCN2 (Homo sapiens)6480464CTDSilicon Dioxide analog results in decreased expression of LCN2 mRNA; Silicon Dioxide results in decreased expression of LCN2 mRNAPMID:25895662 PMID:28425640
Lcn2increases expressionISOLcn2 (Rattus norvegicus)6480464CTDSilicon Dioxide results in increased expression of LCN2 mRNAPMID:22431001
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