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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69453
Species: Homo sapiens
RGD Object: Gene
Symbol: LCN2
Name: lipocalin 2
Acc ID: CHEBI:28757
Term: fructose
Definition: A ketohexose that is an isomer of glucose.
Chemical ID: MESH:D005632
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
LCN2multiple interactionsISOLcn2 (Rattus norvegicus)6480464CTD[dapagliflozin co-treated with Atorvastatin] inhibits the reaction [[Fructose co-treated with Dietary Fats] results in increased expression of LCN2 protein]; [Fructose co-treated with Dietary Fats] results in increased expression of LCN2 protein; [Streptozocin co-treated with Fructose] results in increased expression of LCN2 protein; Atorvastatin inhibits the reaction [[Fructose co-treated with Dietary Fats] results in increased expression of LCN2 protein]; dapagliflozin inhibits the reaction [[Fructose co-treated with Dietary Fats] results in increased expression of LCN2 protein]; dapagliflozin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of LCN2 protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of LCN2 protein]PMID:30551545 PMID:32259528
LCN2multiple interactionsISOLcn2 (Mus musculus)6480464CTD[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of LCN2 mRNAPMID:37567420
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