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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69423
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Srebf1
Name: sterol regulatory element binding transcription factor 1
Acc ID: CHEBI:18123
Term: N-methylnicotinate
Definition: An iminium betaine that is the conjugate base of N-methylnicotinic acid, arising from deprotonation of the carboxy group.
Chemical ID: MESH:C009560
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Srebf1multiple interactionsISOSREBF1 (Homo sapiens)6480464CTDATG7 protein affects the reaction [trigonelline inhibits the reaction [Palmitic Acid results in increased expression of SREBF1 protein]]; trigonelline inhibits the reaction [Palmitic Acid results in increased expression of SREBF1 protein]PMID:30208301
Srebf1multiple interactionsISOSrebf1 (Mus musculus)6480464CTDtrigonelline inhibits the reaction [[Cholesterol, Dietary co-treated with Dietary Fats] results in increased expression of SREBF1 protein]; trigonelline inhibits the reaction [Palmitic Acid results in increased expression of SREBF1 protein]PMID:30208301
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