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GENE - TERM ANNOTATION REPORT

RGD ID: 69408
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Lcn2
Name: lipocalin 2
Acc ID: DOID:3021
Term: acute kidney failure
Definition: Abrupt reduction in kidney function. Acute kidney injury encompasses the entire spectrum of the syndrome including acute kidney failure; ACUTE KIDNEY TUBULAR NECROSIS; and other less severe conditions.
Definition Source(s): MESH:D058186
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Lcn2 IEP 7244370RGDprotein:increased expression:urine 
Lcn2 ISOLCN2 (Homo sapiens)125973912RGDassociated with open cardiac surgeries;protein:increased expression:urine: 
Lcn2 ISOLCN2 (Homo sapiens)126781714RGDprotein:increased expression:urine 
Lcn2 ISOLCN2 (Homo sapiens)11554173CTDCTD Direct Evidence: marker/mechanismPMID:20623750 PMID:22005293 PMID:23052191 PMID:27888128 PMID:28885000
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