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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69329
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Mapt
Name: microtubule-associated protein tau
Acc ID: CHEBI:176788
Term: dizocilpine maleate
Definition: A maleate salt obtained by reaction of dizocilpine with one equivalent of maleic acid.
Chemical ID: MESH:D016291
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Maptmultiple interactionsEXP 6480464CTDDizocilpine Maleate inhibits the reaction [D-Aspartic Acid results in decreased expression of and affects the phosphorylation of MAPT protein]; Dizocilpine Maleate inhibits the reaction [D-Aspartic Acid results in decreased phosphorylation of MAPT protein]; Dizocilpine Maleate inhibits the reaction [D-Aspartic Acid results in increased cleavage of MAPT protein]PMID:30822420
Maptmultiple interactionsISOMAPT (Homo sapiens)6480464CTDDizocilpine Maleate inhibits the reaction [Methylmercury Compounds results in increased phosphorylation of MAPT protein]PMID:21976409
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