GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Mapt | multiple interactions | EXP | | 6480464 | CTD | [BDNF protein co-treated with MF63 compound co-treated with Estradiol] inhibits the reaction [Paraquat results in increased phosphorylation of MAPT protein]; [BDNF protein co-treated with MF63 compound] promotes the reaction [Estradiol inhibits the reaction [Paraquat results in increased phosphorylation of MAPT protein]]; Estradiol inhibits the reaction [Paraquat results in increased phosphorylation of MAPT protein] | PMID:31715309 PMID:32738378 | Mapt | increases expression | ISO | MAPT (Homo sapiens) | 6480464 | CTD | Estradiol results in increased expression of MAPT mRNA; Estradiol results in increased expression of MAPT protein | PMID:20579400 PMID:31614463 | Mapt | increases phosphorylation | ISO | MAPT (Homo sapiens) | 6480464 | CTD | Estradiol results in increased phosphorylation of MAPT protein | PMID:27026707 | Mapt | multiple interactions | ISO | MAPT (Homo sapiens) | 6480464 | CTD | Tamoxifen inhibits the reaction [Estradiol results in increased expression of MAPT protein] | PMID:20579400 | | ||||||||||||||||||||||
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