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GENE - TERM ANNOTATION REPORT

RGD ID: 69298
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Enpp2
Name: ectonucleotide pyrophosphatase/phosphodiesterase 2
Acc ID: GO:0005044
Term: scavenger receptor activity
Definition: Combining with any modified low-density lipoprotein (LDL) or other polyanionic ligand and delivering the ligand into the cell via endocytosis. Ligands include acetylated and oxidized LDL, Gram-positive and Gram-negative bacteria, apoptotic cells, amyloid-beta fibrils, and advanced glycation end products (AGEs).
Definition Source(s): GOC:bf, PMID:11790542, PMID:12379907, PMID:12621157, PMID:20981357
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Enpp2enablesIEAInterPro:IPR0204361600115InterProGO_REF:0000002

GO_REF:0000002
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