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RGD ID: 69270
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Slc5a7
Name: solute carrier family 5 member 7
Acc ID: GO:0007271
Term: synaptic transmission, cholinergic
Definition: The vesicular release of acetylcholine from a presynapse, across a chemical synapse, the subsequent activation of dopamine receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse.
Definition Source(s): GOC:dos, Wikipedia:Cholinergic
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
 IBAMGI:MGI:1927126, PANTHER:PTN00021340313792537GO_CentralPMID:21873635

 IEAUniProtKB:Q8BGY9, ensembl:ENSMUSP000000933791600115EnsemblGO_REF:0000107

 ISORGD:7368941624291RGDMGI:MGI:3045463 (MGI:MGI:3044863, PMID:15173594), (MGI:MGI:3590443, PMID:16162937)

MGI:MGI:3044863, MGI:MGI:3590443, PMID:15173594, PMID:16162937
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.