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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69270
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Slc5a7
Name: solute carrier family 5 member 7
Acc ID: CHEBI:10138
Term: [6]-Shogaol
Definition: A monomethoxybenzene that has formula C17H24O3.
Chemical ID: MESH:C040115
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases expressionISORGD:7368946480464CTD[shogaol results in increased expression of BDNF protein] which results in increased expression of SLC5A7 protein, shogaol results in increased expression of SLC5A7 protein

PMID:22381256
multiple interactionsISORGD:7368946480464CTD[shogaol co-treated with Hydrogen Peroxide] results in increased expression of SLC5A7 protein, shogaol inhibits the reaction [Hydrogen Peroxide results in decreased expression of SLC5A7 protein], staurosporine aglycone inhibits the reaction [[shogaol co-treated with Hydrogen Peroxide] results in increased expression of SLC5A7 protein]

PMID:22381256
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.