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GENE - TERM ANNOTATION REPORT

RGD ID: 69250
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Wnt5a
Name: Wnt family member 5A
Acc ID: GO:0090179
Term: planar cell polarity pathway involved in neural tube closure
Definition: The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors that modulates the establishment of planar polarity contributing to neural tube closure.
Definition Source(s): GOC:ascb_2009, GOC:dph, GOC:tb
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Wnt5aacts_upstream_of_or_withinISOWnt5a (Mus musculus)1624291RGDMGI:1857617 PMID:19056682

PMID:19056682
Wnt5ainvolved_inIEAUniProtKB:P22725 or ensembl:ENSMUSP000000648781600115EnsemblGO_REF:0000107

GO_REF:0000107
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