GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Wnt5a | decreases expression | EXP | | 6480464 | CTD | Silicon Dioxide results in decreased expression of WNT5A mRNA | PMID:32721576 | Wnt5a | decreases expression | ISO | WNT5A (Homo sapiens) | 6480464 | CTD | Silicon Dioxide analog results in decreased expression of WNT5A mRNA; Silicon Dioxide results in decreased expression of WNT5A mRNA; Silicon Dioxide results in decreased expression of WNT5A protein | PMID:23806026 PMID:25351596 PMID:27095093 | Wnt5a | increases expression | ISO | Wnt5a (Mus musculus) | 6480464 | CTD | Silicon Dioxide results in increased expression of WNT5A protein | PMID:37075931 | Wnt5a | multiple interactions | ISO | Wnt5a (Mus musculus) | 6480464 | CTD | erastin promotes the reaction [Silicon Dioxide results in increased expression of WNT5A protein]; ferrostatin-1 inhibits the reaction [Silicon Dioxide results in increased expression of WNT5A protein]; KN 93 inhibits the reaction [Silicon Dioxide results in increased expression of WNT5A protein]; WNT5A protein promotes the reaction [Silicon Dioxide results in decreased expression of GPX4 protein]; WNT5A protein promotes the reaction [Silicon Dioxide results in decreased expression of SLC7A11 protein]; WNT5A protein promotes the reaction [Silicon Dioxide results in increased expression of DDIT3 protein]; WNT5A protein promotes the reaction [Silicon Dioxide results in increased expression of NFATC2 protein] | PMID:37075931 | | ||||||||||||||||||||||
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