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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69247
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Kcnj11
Name: potassium inwardly-rectifying channel, subfamily J, member 11
Acc ID: CHEBI:15422
Term: ATP
Definition: An adenosine 5'-phosphate in which the 5'-phosphate is a triphosphate group. It is involved in the transportation of chemical energy during metabolic pathways.
Chemical ID: MESH:D000255
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Kcnj11decreases response to substanceISOKcnj11 (Mus musculus)6480464CTDKCNJ11 protein mutant form results in decreased susceptibility to Adenosine TriphosphatePMID:28842488
Kcnj11multiple interactionsISOKcnj11 (Mus musculus)6480464CTDAdenosine Monophosphate inhibits the reaction [Adenosine Triphosphate results in decreased activity of [KCNJ11 protein binds to ABCC9 protein]]; Adenosine Triphosphate results in decreased activity of [KCNJ11 protein binds to ABCC9 protein]; Creatine metabolite inhibits the reaction [Adenosine Monophosphate inhibits the reaction [Adenosine Triphosphate results in decreased activity of [KCNJ11 protein binds to ABCC9 protein]]]PMID:11390963 PMID:28842488
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