GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Aldh2 | decreases activity | EXP | | 6480464 | CTD | Disulfiram metabolite results in decreased activity of ALDH2 protein; Disulfiram results in decreased activity of ALDH2 protein | PMID:10513990 PMID:9585485 | Aldh2 | decreases activity | ISO | Aldh2 (Rattus norvegicus) | 6480464 | CTD | Disulfiram results in decreased activity of ALDH2 protein | PMID:11142365 PMID:24496638 | Aldh2 | decreases activity | ISO | ALDH2 (Homo sapiens) | 6480464 | CTD | Disulfiram results in decreased activity of ALDH2 protein | PMID:22079344 | Aldh2 | decreases expression | ISO | Aldh2 (Rattus norvegicus) | 6480464 | CTD | Disulfiram results in decreased expression of ALDH2 mRNA | PMID:24496638 | Aldh2 | multiple interactions | ISO | Aldh2 (Rattus norvegicus) | 6480464 | CTD | [Disulfiram results in decreased activity of ALDH2 protein] which results in increased susceptibility to Glyceraldehyde; [Disulfiram results in decreased activity of ALDH2 protein] which results in increased susceptibility to glycolaldehyde; [Disulfiram results in decreased activity of ALDH2 protein] which results in increased susceptibility to Glyoxal; [Disulfiram results in decreased activity of ALDH2 protein] which results in increased susceptibility to hydroxypyruvic acid; [Disulfiram results in decreased activity of ALDH2 protein] which results in increased susceptibility to Pyruvaldehyde | PMID:21334317 PMID:21376711 | | ||||||||||||||||||||||
| Go Back to source page | Continue to Ontology report |