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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69218
Species: Mus musculus
RGD Object: Gene
Symbol: Aldh2
Name: aldehyde dehydrogenase 2, mitochondrial
Acc ID: CHEBI:16698
Term: cyanamide
Definition: A nitrile that is hydrogen cyanide in which the hydrogen has been replaced by an amino group.
Chemical ID: MESH:D003484
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Aldh2decreases activityISOAldh2 (Rattus norvegicus)6480464CTDCyanamide results in decreased activity of ALDH2 proteinPMID:14690875 PMID:19576883
Aldh2multiple interactionsISOAldh2 (Rattus norvegicus)6480464CTDCyanamide affects the reaction [[lead acetate results in increased abundance of Lead] affects the reaction [Ethanol affects the expression of ALDH2 protein]]; Cyanamide affects the reaction [[lead acetate results in increased abundance of Lead] which affects the expression of ALDH2 protein]; Cyanamide affects the reaction [Ethanol affects the expression of ALDH2 protein]PMID:31550440
Aldh2multiple interactionsISOALDH2 (Homo sapiens)6480464CTD[Cyanamide results in decreased activity of ALDH2 protein] which results in decreased metabolism of NitroglycerinPMID:18272654
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