GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | ESR2 | affects binding | EXP | | 6480464 | CTD | 4-tert-octylphenol binds to ESR2 protein | PMID:10964929 PMID:12161000 PMID:12224631 PMID:19913605 | ESR2 | increases expression | EXP | | 6480464 | CTD | 4-tert-octylphenol results in increased expression of ESR2 mRNA | PMID:12737316 | ESR2 | multiple interactions | EXP | | 6480464 | CTD | 4-tert-octylphenol binds to and results in increased activity of ESR2 protein; 4-tert-octylphenol inhibits the reaction [Estradiol binds to ESR2 protein]; 4-tert-octylphenol promotes the reaction [ESR2 protein binds to NCOA1 protein]; 4-tert-octylphenol promotes the reaction [ESR2 protein binds to NCOA2 protein] | PMID:10964929 PMID:27633901 PMID:33049310 | |
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