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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69213
Species: Homo sapiens
RGD Object: Gene
Symbol: ESR2
Name: estrogen receptor 2
Acc ID: CHEBI:143794
Term: 3,5,6-trichloro-2-pyridinol
Definition: A hydroxypyridine that is pyridin-2-ol substituted by chloro groups at positions 3,5 and 6. It is a metabolite of the agrochemical chlorpyrifos.
Chemical ID: MESH:C012587
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
ESR2multiple interactionsISOEsr2 (Mus musculus)6480464CTD[diethyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate co-treated with bis(2-propylheptyl)phthalate co-treated with bisphenol A co-treated with 3,5,6-trichloro-2-pyridinol co-treated with 3-phenoxybenzoic acid co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of ESR2 mRNAPMID:32518293
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