GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | UCP2 | increases expression | ISO | Ucp2 (Rattus norvegicus) | 6480464 | CTD | Hydrogen Peroxide results in increased expression of UCP2 protein | PMID:30104959 | UCP2 | multiple interactions | ISO | Ucp2 (Rattus norvegicus) | 6480464 | CTD | [[benzo(a)pyrene-1,6-quinone results in increased abundance of Superoxides] co-treated with [benzo(a)pyrene-1,6-quinone results in decreased abundance of Hydrogen Peroxide]] results in increased expression of UCP2 mRNA; [[pirinixic acid results in increased expression of UCP2 protein] which results in increased abundance of Hydrogen Peroxide] which results in decreased expression of BCL2 protein; [pirinixic acid results in increased expression of UCP2 protein] which results in increased abundance of Hydrogen Peroxide; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased expression of UCP2 protein]; Glutathione inhibits the reaction [[pirinixic acid results in increased expression of UCP2 protein] which results in increased abundance of Hydrogen Peroxide]; Potassium Cyanide promotes the reaction [[pirinixic acid results in increased expression of UCP2 protein] which results in increased abundance of Hydrogen Peroxide]; trilobatin inhibits the reaction [Hydrogen Peroxide results in increased expression of UCP2 protein] | PMID:10860543 PMID:19361538 PMID:30104959 | | ||||||||||||||||||||||
| Go Back to source page | Continue to Ontology report |