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GENE - TERM ANNOTATION REPORT

RGD ID: 69169
Species: Mus musculus
RGD Object: Gene
Symbol: Pparg
Name: peroxisome proliferator activated receptor gamma
Acc ID: DOID:9007692
Term: Insulin Resistance
Definition: Diminished effectiveness of INSULIN in lowering blood sugar levels: requiring the use of 200 units or more of insulin per day to prevent HYPERGLYCEMIA or KETOSIS.
Definition Source(s): MESH:D007333
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Pparg ISOPPARG (Homo sapiens)1601446RGDDNA:nonsense mutation 
Pparg ISOPPARG (Homo sapiens)11554173CTDCTD Direct Evidence: therapeuticPMID:16168052 PMID:21354099 PMID:21484566
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