GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Pparg | decreases expression | EXP | | 6480464 | CTD | Methamphetamine results in decreased expression of PPARG protein | PMID:18946735 | Pparg | increases activity | EXP | | 6480464 | CTD | Methamphetamine results in increased activity of PPARG protein | PMID:17019405 | Pparg | increases expression | EXP | | 6480464 | CTD | Methamphetamine results in increased expression of PPARG protein | PMID:17019405 | Pparg | increases response to substance | EXP | | 6480464 | CTD | PPARG protein results in increased susceptibility to Methamphetamine | PMID:17019405 | Pparg | multiple interactions | EXP | | 6480464 | CTD | 2-chloro-5-nitrobenzanilide promotes the reaction [PPARG protein results in increased susceptibility to Methamphetamine]; [pioglitazone co-treated with alitretinoin] inhibits the reaction [PPARG protein results in increased susceptibility to Methamphetamine]; ciglitazone inhibits the reaction [PPARG protein results in increased susceptibility to Methamphetamine]; Ibuprofen inhibits the reaction [Methamphetamine results in decreased expression of PPARG protein]; pioglitazone inhibits the reaction [PPARG protein results in increased susceptibility to Methamphetamine] | PMID:17019405 PMID:18946735 | |
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