GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | DDIT3 | multiple interactions | EXP | | 6480464 | CTD | [Galactose co-treated with Glucose deficiency] promotes the reaction [leflunomide results in increased expression of DDIT3 protein] | PMID:29427785 | DDIT3 | decreases expression | ISO | Ddit3 (Rattus norvegicus) | 6480464 | CTD | Glucose results in decreased expression of DDIT3 mRNA | PMID:24349266 | DDIT3 | decreases expression | ISO | Ddit3 (Mus musculus) | 6480464 | CTD | Glucose results in decreased expression of DDIT3 mRNA | PMID:17178593 | DDIT3 | increases expression | ISO | Ddit3 (Rattus norvegicus) | 6480464 | CTD | Glucose deficiency results in increased expression of DDIT3 protein; Glucose results in increased expression of DDIT3 protein | PMID:21337367 PMID:34801538 | DDIT3 | increases expression | ISO | Ddit3 (Mus musculus) | 6480464 | CTD | Glucose deficiency results in increased expression of DDIT3 mRNA; Glucose results in increased expression of DDIT3 mRNA; Glucose results in increased expression of DDIT3 protein | PMID:27226639 PMID:28482072 PMID:30076216 | DDIT3 | multiple interactions | ISO | Ddit3 (Rattus norvegicus) | 6480464 | CTD | Chlorogenic Acid inhibits the reaction [Glucose results in increased expression of DDIT3 protein]; Metformin inhibits the reaction [Glucose results in increased expression of DDIT3 protein] | PMID:34801538 | DDIT3 | multiple interactions | ISO | Ddit3 (Mus musculus) | 6480464 | CTD | 2-aminoethoxydiphenyl borate inhibits the reaction [Glucose results in increased expression of DDIT3 protein]; DDIT3 affects the reaction [Glucose results in decreased expression of PPARGC1A mRNA]; Gadolinium inhibits the reaction [Glucose results in increased expression of DDIT3 protein]; Glucose inhibits the reaction [DDIT3 protein binds to PPARGC1A promoter]; TRPM7 protein affects the reaction [Glucose results in increased expression of DDIT3 protein]; waixenicin A inhibits the reaction [Glucose results in increased expression of DDIT3 protein] | PMID:28482072 PMID:30076216 | | ||||||||||||||||||||||
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