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GENE - TERM ANNOTATION REPORT

RGD ID: 69152
Species: Homo sapiens
RGD Object: Gene
Symbol: EGFR
Name: epidermal growth factor receptor
Acc ID: DOID:3908
Term: lung non-small cell carcinoma
Definition: A lung carcinoma that is characterized as any type of epithelial lung cancer other than small cell lung carcinoma. (DO)
Definition Source(s): http://en.wikipedia.org/wiki/Non-small-cell_lung_carcinoma "DO" "DO"
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
EGFR IAGP 1601010RGDDNA:deletion:cds:2240del18 (human) 
EGFRamelioratesIEP 151357000RGDhuman cells in mouse model 
EGFRamelioratesIEP 153344584RGDhuman cells in mouse model 
EGFRseverityIEP 126790479RGD  
EGFRsusceptibilityIEP 5131640RGDprotein:decreased expression:tumor (human) 
EGFR IMP 5131629RGD  
EGFRtreatmentIMP 13464349RGD  
EGFR TAS 5133241RGD  
EGFR TAS 5133242RGD  
EGFR EXP 11554173CTDCTD Direct Evidence: marker/mechanismPMID:21336183 PMID:21440325 PMID:21478906 PMID:21777763 PMID:21782507 PMID:21791641 PMID:21904575 PMID:21933749 PMID:22286583 PMID:22617245 PMID:22751098 PMID:22787409 PMID:22787412 PMID:22948846 PMID:23435014 PMID:24467950
EGFR IAGP (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: Non-small cell lung carcinomaPMID:22753918 PMID:23102728 PMID:23945392 PMID:25157968 PMID:26619011
EGFR IAGP (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: Non-small cell lung carcinomaPMID:25157968
EGFR IAGP (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: Non-small cell lung carcinomaPMID:18628075 PMID:25157968
EGFR IAGP (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: Non-small cell lung carcinomaPMID:19147750 PMID:25157968
EGFR IAGP (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: Non-small cell lung carcinomaPMID:19455431 PMID:25157968
EGFR IAGP (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: Non-small cell lung carcinomaPMID:19147750 PMID:23800712 PMID:25157968 PMID:27294619 PMID:28492532
EGFR IAGP (Homo sapiens) or (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: Non-small cell lung carcinomaPMID:23485129 PMID:25157968
EGFR IAGP (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: Non-small cell lung carcinomaPMID:18089823 PMID:24934779 PMID:25157968
EGFR IAGP (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: Non-small cell lung carcinomaPMID:25939061 PMID:25948633 PMID:28492532
EGFR IAGP (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: Non-small cell lung cancerPMID:15118073 PMID:15118125 PMID:15329413 PMID:15897572 PMID:15901872 PMID:16115929 PMID:16203769 PMID:16204011 PMID:16204070 PMID:16865253 PMID:16956694 PMID:17047654 PMID:17106442 PMID:17192902 PMID:17285735 PMID:17317677 PMID:17387341 PMID:17429313 PMID:17473659 PMID:18303429 PMID:19096302 PMID:19455431 PMID:19692680 PMID:19692684 PMID:19922469 PMID:20022809 PMID:20038723 PMID:20479403 PMID:20573926 PMID:21670455 PMID:21783417 PMID:21900837 PMID:22215752 PMID:22285168 PMID:22370314 PMID:22452895 PMID:22753918 PMID:22760226 PMID:22992668 PMID:23102728 PMID:23816960 PMID:23948351 PMID:25157968 PMID:26490356 PMID:26619011 PMID:27993330
EGFR IAGP (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: Non-small cell lung cancerPMID:11423618 PMID:15118073 PMID:15118125 PMID:15272417 PMID:15329413 PMID:15728811 PMID:15737014 PMID:15901872 PMID:16258541 PMID:16912157 PMID:17020982 PMID:17085664 PMID:17332364 PMID:17510392 PMID:17726540 PMID:18093943 PMID:18227510 PMID:18596266 PMID:18981003 PMID:18992959 PMID:19096324 PMID:19381876 PMID:19589612 PMID:20033049 PMID:20068085 PMID:20129249 PMID:21194487 PMID:21233402 PMID:21248300 PMID:21252721 PMID:21430269 PMID:21531810 PMID:21921847 PMID:22215752 PMID:22452896 PMID:22588155 PMID:22992668 PMID:23102728 PMID:23540867 PMID:23816963 PMID:24065731 PMID:24202392 PMID:24453288 PMID:24478319 PMID:24623981 PMID:24636847 PMID:24658966 PMID:24729716 PMID:24736066 PMID:24736080 PMID:24893891 PMID:25157968 PMID:25668228 PMID:25741868 PMID:25923549 PMID:25923550 PMID:26515464 PMID:26700910 PMID:26720284 PMID:28492532 PMID:28947568 PMID:30610926 PMID:33858029
EGFR IAGP (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: Non-small cell lung carcinomaPMID:18450321 PMID:24033266
EGFR IAGP (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: Non-small cell lung carcinomaPMID:15118073 PMID:15118125 PMID:15788655 PMID:24712396
EGFR IAGP (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: Nonsmall cell lung cancer, response to tyrosine kinase inhibitor in, somaticPMID:15118073 PMID:15118125 PMID:15329413 PMID:15710947 PMID:16011858 PMID:16115929 PMID:18199554 PMID:19536777 PMID:19671738 PMID:19922469 PMID:20479403 PMID:21841502 PMID:22753918 PMID:23102728 PMID:25157968 PMID:26619011
EGFR IAGP (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: Non-small cell lung carcinomaPMID:15118073 PMID:15118125 PMID:15329413 PMID:15710947 PMID:15738541 PMID:16011858 PMID:16115929 PMID:18458038 PMID:19922469 PMID:20479403 PMID:21531810 PMID:22753918 PMID:2302402 PMID:23102728 PMID:23242437 PMID:24033266 PMID:25157968 PMID:26619011 PMID:31396478
EGFR IAGP (Homo sapiens) or (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: Non-small cell lung carcinoma 
EGFR IAGP (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: Non-small cell lung carcinomaPMID:15737014 PMID:22622260 PMID:25157968
EGFR IAGP (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: Non-small cell lung carcinomaPMID:16730855 PMID:17085664 PMID:17192902 PMID:17545553 PMID:25157968
EGFR IAGP (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: Non-small cell lung carcinomaPMID:18372921 PMID:24033266
EGFR IAGP (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: Non-small cell lung carcinomaPMID:15623594 PMID:16205628 PMID:16707764 PMID:16863509 PMID:17653080 PMID:19147750 PMID:19536777 PMID:20522446 PMID:22753918 PMID:23102728 PMID:24033266 PMID:25157968 PMID:25521405 PMID:26051236 PMID:29141884
EGFR IAGP (Homo sapiens) or (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: Non-small cell lung cancer | ClinVar Annotator: match by term: Non-small cell lung carcinomaPMID:16187797 PMID:24033266
EGFR IAGP (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: Non-small cell lung carcinomaPMID:16187797 PMID:19096302 PMID:21572125 PMID:24033266
EGFR IAGP (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: Non-small cell lung carcinomaPMID:16187797 PMID:16533793
EGFR IAGP (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: Non-small cell lung carcinomaPMID:16187797
EGFR IAGP (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: Non-small cell lung carcinomaPMID:16533793 PMID:18176089 PMID:24033266
EGFR IAGP (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: Non-small cell lung carcinomaPMID:15681531 PMID:16533793 PMID:19455431 PMID:21718596 PMID:24033266 PMID:25157968
EGFR IAGP (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: Non-small cell lung carcinomaPMID:23242437 PMID:23358982 PMID:24712396 PMID:25382819 PMID:25741868 PMID:25969368 PMID:26101090 PMID:28492532 PMID:28874603 PMID:29576263 PMID:29945477 PMID:33644199 PMID:33898318 PMID:34555730 PMID:36698436
EGFR IAGP (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: Nonsmall cell lung cancer, response to tyrosine kinase inhibitor in, somaticPMID:15118073 PMID:15118125 PMID:15728811
EGFR IAGP (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: Non-small cell lung cancerPMID:15118073 PMID:15118125 PMID:15329413 PMID:15604253 PMID:15625347 PMID:15710947 PMID:15741570 PMID:15998907 PMID:16011858 PMID:16105816 PMID:16115929 PMID:16187797 PMID:16199108 PMID:16204070 PMID:16467085 PMID:16533793 PMID:17192902 PMID:17285735 PMID:17473653 PMID:17904685 PMID:18176089 PMID:18325048 PMID:18334834 PMID:18948947 PMID:19536777 PMID:19922469 PMID:20479403 PMID:20559149 PMID:20808254 PMID:21057810 PMID:21317742 PMID:21527506 PMID:21592614 PMID:21841502 PMID:21899495 PMID:22019513 PMID:22753918 PMID:22809298 PMID:23102728 PMID:23468066 PMID:24033266 PMID:24039832 PMID:24894453 PMID:25061320 PMID:25157968 PMID:28492532 PMID:29100434
EGFR IAGP (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: Non-small cell lung cancerPMID:15118073 PMID:15118125 PMID:15329413 PMID:15897572 PMID:19922469 PMID:22753918 PMID:23102728 PMID:26619011
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