GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | CASP9 | increases activity | EXP | | 6480464 | CTD | Pyruvaldehyde results in increased activity of CASP9 protein | PMID:31254498 | CASP9 | increases cleavage | EXP | | 6480464 | CTD | Pyruvaldehyde results in increased cleavage of CASP9 protein | PMID:33930484 | CASP9 | increases expression | EXP | | 6480464 | CTD | Pyruvaldehyde results in increased expression of CASP9 protein | PMID:26577515 | CASP9 | multiple interactions | EXP | | 6480464 | CTD | 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [salvin inhibits the reaction [Pyruvaldehyde results in increased expression of CASP9 protein]]; naringenin inhibits the reaction [Pyruvaldehyde results in increased activity of CASP9 protein]; pimagedine inhibits the reaction [Pyruvaldehyde results in increased cleavage of CASP9 protein]; pterostilbene inhibits the reaction [Pyruvaldehyde results in increased cleavage of CASP9 protein]; salvin inhibits the reaction [Pyruvaldehyde results in increased expression of CASP9 protein] | PMID:26577515 PMID:31254498 PMID:33930484 | CASP9 | decreases expression | ISO | Casp9 (Rattus norvegicus) | 6480464 | CTD | Pyruvaldehyde results in decreased expression of CASP9 protein | PMID:34455488 | CASP9 | multiple interactions | ISO | Casp9 (Rattus norvegicus) | 6480464 | CTD | Phosphocreatine inhibits the reaction [Pyruvaldehyde results in decreased expression of CASP9 protein] | PMID:34455488 | | ||||||||||||||||||||||
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