GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | NPPB | increases expression | EXP | | 6480464 | CTD | Doxorubicin results in increased expression of NPPB mRNA; Doxorubicin results in increased expression of NPPB protein | PMID:11466716 PMID:11724646 PMID:29803840 PMID:30031762 PMID:32185414 | NPPB | decreases expression | ISO | Nppb (Mus musculus) | 6480464 | CTD | Doxorubicin results in decreased expression of NPPB mRNA | PMID:17531194 | NPPB | decreases expression | ISO | Nppb (Rattus norvegicus) | 6480464 | CTD | Doxorubicin results in decreased expression of NPPB mRNA | PMID:19796650 | NPPB | increases expression | ISO | Nppb (Mus musculus) | 6480464 | CTD | Doxorubicin results in increased expression of NPPB mRNA | PMID:16770644 PMID:28608983 PMID:32434049 PMID:36227756 | NPPB | increases expression | ISO | Nppb (Rattus norvegicus) | 6480464 | CTD | Doxorubicin results in increased expression of NPPB mRNA; Doxorubicin results in increased expression of NPPB protein; Doxorubicin results in increased expression of NPPB protein alternative form; Doxorubicin results in increased expression of NPPB protein modified form | PMID:14745153 PMID:26036690 PMID:26721193 PMID:32185414 PMID:32691977 PMID:34015281 PMID:34369273 PMID:34813134 PMID:35093381 PMID:35152301 | NPPB | multiple interactions | ISO | Nppb (Mus musculus) | 6480464 | CTD | Folic Acid inhibits the reaction [Doxorubicin results in increased expression of NPPB mRNA]; PRKN protein affects the reaction [Doxorubicin results in increased expression of NPPB mRNA] | PMID:28608983 PMID:32434049 | NPPB | multiple interactions | ISO | Nppb (Rattus norvegicus) | 6480464 | CTD | Carvedilol inhibits the reaction [Doxorubicin results in increased expression of NPPB protein]; citronellal inhibits the reaction [Doxorubicin results in increased expression of NPPB protein]; corilagin inhibits the reaction [Doxorubicin results in increased expression of NPPB protein]; Doxorubicin inhibits the reaction [phenylhydrazine results in increased expression of NPPB mRNA]; Febuxostat inhibits the reaction [Doxorubicin results in increased expression of NPPB protein]; Lithium Chloride inhibits the reaction [citronellal inhibits the reaction [Doxorubicin results in increased expression of NPPB protein]]; Melatonin inhibits the reaction [Doxorubicin results in increased expression of NPPB protein]; plumbagin inhibits the reaction [Doxorubicin results in increased expression of NPPB protein]; sacubitril and valsartan sodium hydrate drug combination inhibits the reaction [Doxorubicin results in increased expression of NPPB protein alternative form]; Verteporfin inhibits the reaction [Melatonin inhibits the reaction [Doxorubicin results in increased expression of NPPB protein]]; YAP1 protein affects the reaction [Melatonin inhibits the reaction [Doxorubicin results in increased expression of NPPB protein]] | PMID:22908232 PMID:26036690 PMID:32691977 PMID:34369273 PMID:34813134 PMID:35093381 PMID:35152301 | | ||||||||||||||||||||||
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