GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | CDKN1B | increases expression | EXP | | 6480464 | CTD | Resveratrol results in increased expression of CDKN1B mRNA; Resveratrol results in increased expression of CDKN1B protein | PMID:15829497 PMID:16761963 PMID:17050787 PMID:17088997 PMID:17804756 PMID:18089832 PMID:18347188 PMID:20504360 PMID:21179458 PMID:21209944 PMID:21980390 PMID:22029423 PMID:24331535 PMID:25672876 | CDKN1B | multiple interactions | EXP | | 6480464 | CTD | [Plant Extracts co-treated with Resveratrol] results in increased expression of CDKN1B mRNA; [Resveratrol co-treated with 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one] results in increased expression of CDKN1B protein; FOXO1 protein affects the reaction [Resveratrol results in increased expression of CDKN1B protein]; FOXO3 protein affects the reaction [Resveratrol results in increased expression of CDKN1B protein]; FOXO4 protein affects the reaction [Resveratrol results in increased expression of CDKN1B protein]; Resveratrol inhibits the reaction [cudraflavone B results in increased expression of CDKN1B protein]; Resveratrol inhibits the reaction [Methylcholanthrene results in increased expression of CDKN1B protein]; Resveratrol promotes the reaction [FOXO3 protein binds to CDKN1B promoter] | PMID:17513867 PMID:18022818 PMID:21179458 PMID:23557933 PMID:23881456 | CDKN1B | decreases expression | ISO | Cdkn1b (Rattus norvegicus) | 6480464 | CTD | resveratrol results in decreased expression of CDKN1B mRNA | PMID:25905778 | CDKN1B | increases expression | ISO | Cdkn1b (Mus musculus) | 6480464 | CTD | resveratrol results in increased expression of CDKN1B protein | PMID:21980390 | CDKN1B | multiple interactions | ISO | Cdkn1b (Rattus norvegicus) | 6480464 | CTD | resveratrol inhibits the reaction [Glucose results in increased expression of CDKN1B protein]; SIRT1 protein promotes the reaction [resveratrol inhibits the reaction [Glucose results in increased expression of CDKN1B protein]] | PMID:22561310 | |
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