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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69106
Species: Mus musculus
RGD Object: Gene
Symbol: Nr1i2
Name: nuclear receptor subfamily 1, group I, member 2
Acc ID: CHEBI:9665
Term: triadimefon
Definition: A racemate comprising equal amounts of (R)- and (S)-triadimefon. A fungicide used to control powdery mildew, rusts and other infections in crops.
Chemical ID: MESH:C032910
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nr1i2multiple interactionsEXP 6480464CTDtriadimefon binds to and results in increased activity of NR1I2 proteinPMID:21115097
Nr1i2multiple interactionsISONR1I2 (Homo sapiens)6480464CTD[N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide co-treated with pyrimethanil co-treated with Fenitrothion co-treated with triadimefon co-treated with quinoxyfen co-treated with penconazole] results in increased activity of NR1I2 protein; triadimefon binds to and results in increased activity of NR1I2 proteinPMID:21115097 PMID:25028461
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