GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Jak1 | increases expression | EXP | | 6480464 | CTD | sodium arsenite results in increased expression of JAK1 mRNA | PMID:36209798 | Jak1 | decreases expression | ISO | JAK1 (Homo sapiens) | 6480464 | CTD | sodium arsenite results in decreased expression of JAK1 mRNA | PMID:12679051 PMID:34032870 | Jak1 | multiple interactions | ISO | JAK1 (Homo sapiens) | 6480464 | CTD | sodium arsenite inhibits the reaction [IFNG protein results in increased activity of JAK1 protein]; sodium arsenite inhibits the reaction [IL6 protein results in increased activity of JAK1 protein]; sodium arsenite inhibits the reaction [IL6 protein results in increased phosphorylation of JAK1 protein]; sodium arsenite inhibits the reaction [JAK1 protein results in increased phosphorylation of STAT3 protein]; sodium arsenite results in decreased phosphorylation of and results in decreased activity of JAK1 protein | PMID:15116095 | | ||||||||||||||||||||||
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