GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Tgfb1 | multiple interactions | EXP | | 6480464 | CTD | SB 203580 inhibits the reaction [Silicon Dioxide results in increased expression of TGFB1 protein]; SB 203580 inhibits the reaction [TGFB1 protein inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of and results in decreased secretion of IGF1 protein]]; SB 203580 inhibits the reaction [TGFB1 protein inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of and results in increased secretion of IL1B protein]]; SB 203580 inhibits the reaction [TGFB1 protein inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of and results in increased secretion of TNF protein]]; SB 203580 inhibits the reaction [TGFB1 protein inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of ITGAM protein]]; SB 203580 inhibits the reaction [TGFB1 protein inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of NOS2 protein]] | PMID:19778233 PMID:26254549 | Tgfb1 | multiple interactions | ISO | Tgfb1 (Rattus norvegicus) | 6480464 | CTD | SB 203580 inhibits the reaction [[Calcitriol co-treated with TGFB1 protein] results in increased secretion of VEGFA protein]; SB 203580 inhibits the reaction [TGFB1 protein results in increased secretion of VEGFA protein]; SB 203580 inhibits the reaction [Vehicle Emissions results in increased expression of TGFB1 mRNA] | PMID:12649123 PMID:16598785 | Tgfb1 | multiple interactions | ISO | TGFB1 (Homo sapiens) | 6480464 | CTD | SB 203580 analog inhibits the reaction [TGFB1 protein results in increased expression of CCN2 protein]; SB 203580 inhibits the reaction [Asbestos, Serpentine results in increased secretion of TGFB1 protein]; SB 203580 inhibits the reaction [nickel monoxide results in increased expression of TGFB1 protein]; SB 203580 inhibits the reaction [TGFB1 protein affects the localization of JUNB protein]; SB 203580 inhibits the reaction [TGFB1 protein results in decreased expression of CCND1 protein]; SB 203580 inhibits the reaction [TGFB1 protein results in decreased expression of CDH1 protein]; SB 203580 inhibits the reaction [TGFB1 protein results in decreased expression of KLF5 mRNA]; SB 203580 inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 protein]; SB 203580 inhibits the reaction [TGFB1 protein results in increased expression of CNN1 protein]; SB 203580 inhibits the reaction [TGFB1 protein results in increased expression of ITGB6 mRNA]; SB 203580 inhibits the reaction [TGFB1 protein results in increased expression of JUNB mRNA]; SB 203580 inhibits the reaction [TGFB1 protein results in increased expression of MIR143]; SB 203580 inhibits the reaction [TGFB1 protein results in increased expression of MIR145]; SB 203580 inhibits the reaction [TGFB1 protein results in increased expression of MYOCD mRNA]; SB 203580 inhibits the reaction [TGFB1 protein results in increased expression of SRF protein]; SB 203580 inhibits the reaction [TGFB1 protein results in increased phosphorylation of ATF2 protein] | PMID:11591817 PMID:21303922 PMID:21712382 PMID:25358858 PMID:26054450 PMID:28694203 PMID:35006638 | | ||||||||||||||||||||||
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