GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Tgfb1 | decreases activity | ISO | Tgfb1 (Rattus norvegicus) | 6480464 | CTD | Phenobarbital results in decreased activity of TGFB1 protein | PMID:11238185 | Tgfb1 | increases expression | ISO | Tgfb1 (Rattus norvegicus) | 6480464 | CTD | Phenobarbital results in increased expression of TGFB1 mRNA; Phenobarbital results in increased expression of TGFB1 protein | PMID:30047161 PMID:8055622 | Tgfb1 | multiple interactions | ISO | Tgfb1 (Rattus norvegicus) | 6480464 | CTD | [Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of TGFB1 protein; myrrh resin analog inhibits the reaction [[Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of TGFB1 protein]; Phenobarbital inhibits the reaction [TGFB1 protein results in increased activity of CASP3 protein]; Plant Extracts inhibits the reaction [[Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of TGFB1 protein]; TGFB1 protein promotes the reaction [Phenobarbital results in increased abundance of Peroxides] | PMID:10200566 PMID:28414157 PMID:9806150 | |
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