GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Tgfb1 | multiple interactions | ISO | TGFB1 (Homo sapiens) | 6480464 | CTD | [tolfenamic acid co-treated with TGFB1 protein] results in increased expression of CDH1 protein; tolfenamic acid affects the reaction [TGFB1 protein affects the expression of HK2 protein]; tolfenamic acid affects the reaction [TGFB1 protein affects the expression of SLC2A1 protein]; tolfenamic acid inhibits the reaction [TGFB1 protein results in decreased expression of CDH1 mRNA]; tolfenamic acid inhibits the reaction [TGFB1 protein results in decreased expression of CDH1 protein]; tolfenamic acid inhibits the reaction [TGFB1 protein results in increased expression of MMP2 protein]; tolfenamic acid inhibits the reaction [TGFB1 protein results in increased expression of SNAI1 mRNA]; tolfenamic acid inhibits the reaction [TGFB1 protein results in increased expression of SNAI1 protein]; tolfenamic acid inhibits the reaction [TGFB1 protein results in increased phosphorylation of SMAD2 protein] | PMID:31381904 | | ||||||||||||||||||||||
| Go Back to source page | Continue to Ontology report |