GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | TGFB1 | multiple interactions | EXP | | 6480464 | CTD | [bisphenol A co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of TGFB1 mRNA; [bisphenol A co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of TGFB1 protein; [Dibutyl Phthalate co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of TGFB1 protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of TGFB1 mRNA; [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of TGFB1 mRNA; Fulvestrant inhibits the reaction [[bisphenol A co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of TGFB1 protein]; TGFB1 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of HGF protein]; TGFB1 protein promotes the reaction [Tetradecanoylphorbol Acetate inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]] | PMID:11728381 PMID:15802798 PMID:16979875 PMID:18434080 PMID:25128825 PMID:30218697 | TGFB1 | affects response to substance | ISO | Tgfb1 (Mus musculus) | 6480464 | CTD | TGFB1 affects the susceptibility to Tetradecanoylphorbol Acetate | PMID:20172950 | TGFB1 | increases activity | ISO | Tgfb1 (Mus musculus) | 6480464 | CTD | Tetradecanoylphorbol Acetate results in increased activity of TGFB1 protein | PMID:20852150 | TGFB1 | increases expression | ISO | Tgfb1 (Mus musculus) | 6480464 | CTD | Tetradecanoylphorbol Acetate results in increased expression of TGFB1 mRNA; Tetradecanoylphorbol Acetate results in increased expression of TGFB1 protein | PMID:10381133 PMID:20172950 PMID:27865421 PMID:8148055 | TGFB1 | multiple interactions | ISO | Tgfb1 (Mus musculus) | 6480464 | CTD | 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of TGFB1 protein]; resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TGFB1 mRNA]; TGFB1 affects the reaction [Tetradecanoylphorbol Acetate results in increased activity of PRKCA protein]; TGFB1 affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of and affects the localization of SMAD2 protein]; TGFB1 affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased phosphorylation of SMAD2 protein]; TGFB1 affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]; TGFB1 affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of S100A8 mRNA]; TGFB1 affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of S100A9 mRNA]; TGFB1 affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of SMAD2 protein]; TGFB1 affects the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of JUN protein]; TGFB1 promotes the reaction [Tetradecanoylphorbol Acetate affects the localization of SMAD2 protein modified form]; TGFB1 promotes the reaction [Tetradecanoylphorbol Acetate results in increased activity of PRKCA protein] | PMID:10381133 PMID:20172950 PMID:20852150 | |
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