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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69058
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Matk
Name: megakaryocyte-associated tyrosine kinase
Acc ID: CHEBI:16412
Term: lipopolysaccharide
Definition: Liposaccharide natural compounds consisting of a trisaccharide repeating unit (two heptose units and octulosonic acid) with oligosaccharide side chains and 3-hydroxytetradecanoic acid units (they are a major constituent of the cell walls of Gram-negative bacteria).
Chemical ID: MESH:D008070
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Matkmultiple interactionsISOMATK (Homo sapiens)6480464CTD[TNFSF11 protein results in increased susceptibility to Lipopolysaccharides] which results in increased expression of MATK protein; EIF2AK2 protein affects the reaction [[TNFSF11 protein results in increased susceptibility to Lipopolysaccharides] which results in increased expression of MATK protein]; GW 506033X inhibits the reaction [[TNFSF11 protein results in increased susceptibility to Lipopolysaccharides] which results in increased expression of MATK protein]PMID:27718290
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