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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69057
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Nr1i2
Name: nuclear receptor subfamily 1, group I, member 2
Acc ID: CHEBI:31206
Term: ammonium chloride
Definition: An inorganic chloride having ammonium as the counterion.
Chemical ID: MESH:D000643
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nr1i2affects expressionEXP 6480464CTDAmmonium Chloride affects the expression of NR1I2 mRNAPMID:16483693
Nr1i2multiple interactionsISONR1I2 (Homo sapiens)6480464CTD[NR1I2 protein affects the susceptibility to Ammonium Chloride] which affects the expression of PRKAB1 protein; NR1I2 protein affects the reaction [Ammonium Chloride affects the expression of and affects the phosphorylation of PRKAB1 protein]; NR1I2 protein affects the reaction [Ammonium Chloride affects the expression of and affects the phosphorylation of TP53 protein]; NR1I2 protein affects the reaction [Ammonium Chloride results in decreased expression of SQSTM1 protein]; NR1I2 protein affects the reaction [Ammonium Chloride results in increased metabolism of MAP1LC3B protein]PMID:29908302
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