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GENE - TERM ANNOTATION REPORT

RGD ID: 69029
Species: Homo sapiens
RGD Object: Gene
Symbol: INSR
Name: insulin receptor
Acc ID: GO:0005899
Term: insulin receptor complex
Definition: A disulfide-bonded, heterotetrameric receptor complex. The alpha chains are entirely extracellular, while each beta chain has one transmembrane domain. The ligand binds to the alpha subunit extracellular domain and the kinase is associated with the beta subunit intracellular domain.
Definition Source(s): ISBN:0198506732
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
INSRpart_ofIMP 150520179BHF-UCL PMID:15069075

PMID:15069075
INSRpart_ofIBAFB:FBgn0283499 or PANTHER:PTN000699611 or UniProtKB:P06213150520179GO_Central GO_REF:0000033
INSRpart_ofIEAPANTHER:PTHR24416:SF535150520179TreeGrafter GO_REF:0000118
INSRpart_ofIDA 150520179UniProt PMID:1898103 PMID:19406747

PMID:1898103 PMID:19406747
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