GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Il13 | increases expression | EXP | | 6480464 | CTD | Lipopolysaccharides results in increased expression of IL13 protein | PMID:27568862 PMID:37477137 | Il13 | increases secretion | EXP | | 6480464 | CTD | Lipopolysaccharides results in increased secretion of IL13 protein | PMID:32800949 | Il13 | multiple interactions | EXP | | 6480464 | CTD | [TNFAIP3 gene mutant form results in increased susceptibility to Lipopolysaccharides] which results in increased secretion of IL13 protein; Clopidogrel inhibits the reaction [Lipopolysaccharides results in increased expression of IL13 mRNA]; coagulin-L inhibits the reaction [Lipopolysaccharides results in increased expression of IL13 protein]; Dexamethasone inhibits the reaction [Lipopolysaccharides results in increased expression of IL13 protein]; goniothalamin inhibits the reaction [Lipopolysaccharides results in increased expression of IL13 protein]; MYD88 protein affects the reaction [[TNFAIP3 gene mutant form results in increased susceptibility to Lipopolysaccharides] which results in increased secretion of IL13 protein] | PMID:19172522 PMID:24453940 PMID:27568862 PMID:37477137 | Il13 | increases expression | ISO | Il13 (Rattus norvegicus) | 6480464 | CTD | Lipopolysaccharides results in increased expression of IL13 protein | PMID:33727093 PMID:37148149 | Il13 | increases expression | ISO | IL13 (Homo sapiens) | 6480464 | CTD | Lipopolysaccharides results in increased expression of IL13 protein | PMID:19020770 PMID:27568862 | Il13 | increases secretion | ISO | IL13 (Homo sapiens) | 6480464 | CTD | Lipopolysaccharides results in increased secretion of IL13 protein | PMID:28065790 PMID:32800949 | Il13 | multiple interactions | ISO | Il13 (Rattus norvegicus) | 6480464 | CTD | gossypin inhibits the reaction [Lipopolysaccharides results in increased expression of IL13 protein] | PMID:37148149 | Il13 | multiple interactions | ISO | IL13 (Homo sapiens) | 6480464 | CTD | [Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides co-treated with IL13 protein co-treated with IL4 protein] affects the phosphorylation of STAT6 protein; [Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides co-treated with IL13 protein co-treated with Nanotubes, Carbon co-treated with IL4 protein] affects the phosphorylation of STAT6 protein; [Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides co-treated with IL13 protein co-treated with Nanotubes, Carbon] affects the phosphorylation of STAT6 protein; [Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides co-treated with IL13 protein] affects the phosphorylation of STAT6 protein; [IL13 protein co-treated with IL4 protein co-treated with Nanotubes, Carbon] inhibits the reaction [[Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides] affects the expression of CASP1 protein]; [IL13 protein co-treated with IL4 protein] inhibits the reaction [[Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides] affects the expression of CASP1 protein]; [IL4 protein co-treated with IL13 protein] inhibits the reaction [Lipopolysaccharides results in decreased expression of PRKD1 protein]; [IL4 protein co-treated with IL13 protein] inhibits the reaction [Lipopolysaccharides results in decreased expression of PRKD3 protein]; [IL4 protein co-treated with IL13 protein] inhibits the reaction [Lipopolysaccharides results in increased expression of PRKD2 protein]; [IL4 protein co-treated with IL13 protein] inhibits the reaction [Nanotubes, Carbon promotes the reaction [[Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides co-treated with Nanotubes, Carbon] affects the expression of CASP1 mRNA]]; [Thimerosal co-treated with Lipopolysaccharides] results in increased secretion of IL13 protein; coagulin-L inhibits the reaction [Lipopolysaccharides results in increased expression of IL13 protein]; Dexamethasone inhibits the reaction [Lipopolysaccharides results in increased expression of IL13 protein]; Glutathione inhibits the reaction [[Thimerosal co-treated with Lipopolysaccharides] results in increased secretion of IL13 protein]; IL13 protein inhibits the reaction [[Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides co-treated with Nanotubes, Carbon] affects the secretion of IL1B protein]; IL13 protein inhibits the reaction [[Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides] affects the expression of CASP1 protein]; Leflunomide inhibits the reaction [[IL13 protein co-treated with IL4 protein] inhibits the reaction [[Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides] affects the expression of and affects the activity of CASP1 protein]]; Triclosan inhibits the reaction [Lipopolysaccharides results in increased expression of IL13 mRNA] | PMID:17079650 PMID:20507366 PMID:26091108 PMID:27568862 PMID:37182445 | | ||||||||||||||||||||||
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