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GENE - TERM ANNOTATION REPORT

RGD ID: 69008
Species: Homo sapiens
RGD Object: Gene
Symbol: IL13
Name: interleukin 13
Acc ID: DOID:4483
Term: rhinitis
Definition: A upper respiratory infectious disease which involves irritation and inflammation of the mucous membrane of the nose due to viruses, bacteria or irritants. The inflammation results in generation of excessive amounts of mucus leading to runny nose, as well as nasal congestion and post-nasal drip. (DO)
Definition Source(s): http://en.wikipedia.org/wiki/Rhinitis "DO" "DO"
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
IL13susceptibilityIAGP 4145534RGDDNA:polymorphism: :rs1800925 (human) 
IL13susceptibilityIAGP 4145767RGDassociated with asthma; DNA:polymorphisms:promoter:c. -1510A>C, -1055C>T (human) 
IL13 ISOIl13 (Rattus norvegicus)4145454RGDmRNA:increased expression:nose 
IL13 ISOIl13 (Mus musculus)4206706RGD  
IL13disease_progressionISOIl13 (Mus musculus)4159171RGD  
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