GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Stat3 | increases expression | EXP | | 6480464 | CTD | Folic Acid results in increased expression of STAT3 mRNA | PMID:25629700 | Stat3 | multiple interactions | EXP | | 6480464 | CTD | Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of STAT3 mRNA] | PMID:22206623 | Stat3 | multiple interactions | ISO | STAT3 (Homo sapiens) | 6480464 | CTD | alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [Folic Acid results in increased phosphorylation of STAT3 protein]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide promotes the reaction [Folic Acid inhibits the reaction [Oxygen deficiency results in increased phosphorylation of STAT3 protein]]; Folic Acid inhibits the reaction [Oxygen deficiency results in increased phosphorylation of STAT3 protein]; Folic Acid results in increased activity of and results in increased phosphorylation of STAT3 protein; FOLR1 protein affects the reaction [Folic Acid results in increased phosphorylation of STAT3 protein]; IL6ST protein affects the reaction [Folic Acid results in increased phosphorylation of STAT3 protein] | PMID:25841994 PMID:29685624 | |
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