GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 68949
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Il13
Name: interleukin 13
Acc ID: CHEBI:27881
Term: resveratrol
Definition: A stilbenol that is stilbene in which the phenyl groups are substituted at positions 3, 5, and 4' by hydroxy groups.
Chemical ID: MESH:C059514
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsEXP 6480464CTDresveratrol inhibits the reaction [dinitrophenyl-human serum albumin conjugate results in increased secretion of IL13 protein]

PMID:26621445
decreases expressionISORGD:690086480464CTDresveratrol results in decreased expression of IL13 mRNA

PMID:23224687
decreases expressionISORGD:690096480464CTDresveratrol results in decreased expression of IL13 protein

PMID:22962611, PMID:22986054
decreases response to substanceISORGD:690086480464CTDresveratrol results in decreased susceptibility to IL13 protein

PMID:22254182
decreases secretionISORGD:690086480464CTDresveratrol results in decreased secretion of IL13 protein

PMID:23251493
multiple interactionsISORGD:690086480464CTDResveratrol inhibits the reaction [IL13 protein results in increased secretion of CCL11 protein]

PMID:22254182
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.