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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 68942
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cacna1g
Name: calcium voltage-gated channel subunit alpha1 G
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cacna1gdecreases expressionEXP 6480464CTDbisphenol A results in decreased expression of CACNA1G mRNAPMID:25181051 PMID:30816183
Cacna1gmultiple interactionsEXP 6480464CTD[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in decreased expression of CACNA1G mRNA; [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in increased expression of CACNA1G mRNAPMID:25607892
Cacna1gdecreases expressionISOCACNA1G (Homo sapiens)6480464CTDbisphenol A results in decreased expression of CACNA1G mRNAPMID:25047013 PMID:27685785
Cacna1gdecreases expressionISOCacna1g (Mus musculus)6480464CTDbisphenol A results in decreased expression of CACNA1G mRNAPMID:30951980
Cacna1gincreases expressionISOCacna1g (Mus musculus)6480464CTDbisphenol A results in increased expression of CACNA1G mRNAPMID:25958630 PMID:32156529 PMID:32370801
Cacna1gmultiple interactionsISOCACNA1G (Homo sapiens)6480464CTD[bisphenol A co-treated with Fulvestrant] results in increased methylation of CACNA1G genePMID:31601247
Cacna1gmultiple interactionsISOCacna1g (Mus musculus)6480464CTDESR1 protein affects the reaction [bisphenol A results in increased expression of CACNA1G mRNA]; ESR2 protein affects the reaction [bisphenol A results in increased expression of CACNA1G mRNA]PMID:25958630
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