Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 68650
Species: Mus musculus
RGD Object: Gene
Symbol: Pde10a
Name: phosphodiesterase 10A
Acc ID: CHEBI:17489
Term: 3',5'-cyclic AMP
Definition: A 3',5'-cyclic purine nucleotide having having adenine as the nucleobase.
Chemical ID: MESH:D000242
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Pde10aincreases hydrolysisISOPDE10A (Homo sapiens)6480464CTDPDE10A protein results in increased hydrolysis of Cyclic AMPPMID:10373451
Pde10amultiple interactionsISOPDE10A (Homo sapiens)6480464CTDCyclic AMP inhibits the reaction [PDE10A protein results in increased hydrolysis of Cyclic GMP]; Cyclic GMP inhibits the reaction [PDE10A protein results in increased hydrolysis of Cyclic AMP]; Dipyridamole inhibits the reaction [PDE10A protein results in increased hydrolysis of Cyclic AMP]PMID:10373451
Go Back to source page   Continue to Ontology report