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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 68639
Species: Mus musculus
RGD Object: Gene
Symbol: Aqp3
Name: aquaporin 3
Acc ID: CHEBI:29375
Term: diprotium oxide
Definition: A water that has formula H2O.
Chemical ID: MESH:D014867
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Aqp3increases expressionISOAqp3 (Rattus norvegicus)6480464CTDWater deficiency results in increased expression of AQP3 mRNA; Water deficiency results in increased expression of AQP3 proteinPMID:15462210 PMID:9124401
Aqp3increases transportISOAqp3 (Rattus norvegicus)6480464CTDAQP3 protein results in increased transport of WaterPMID:22687538
Aqp3increases transportISOAQP3 (Homo sapiens)6480464CTDAQP3 protein results in increased transport of WaterPMID:9124401 PMID:9374739
Aqp3multiple interactionsISOAqp3 (Rattus norvegicus)6480464CTDCopper Sulfate inhibits the reaction [AQP3 protein results in increased transport of Water]; Mercuric Chloride inhibits the reaction [AQP3 protein results in increased transport of Water]PMID:22687538
Aqp3multiple interactionsISOAQP3 (Homo sapiens)6480464CTDDexamethasone promotes the reaction [AQP3 protein results in increased transport of Water]; Mercaptoethanol inhibits the reaction [Mercuric Chloride inhibits the reaction [AQP3 protein results in increased transport of Water]]; Mercuric Chloride inhibits the reaction [AQP3 protein results in increased transport of Water]; Mercuric Chloride inhibits the reaction [Dexamethasone promotes the reaction [AQP3 protein results in increased transport of Water]]PMID:9124401 PMID:9374739
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