GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | CLDN3 | increases abundance | EXP | | 6480464 | CTD | CLDN3 protein results in increased abundance of Copper | PMID:23053666 | CLDN3 | multiple interactions | EXP | | 6480464 | CTD | [CLDN3 protein results in increased abundance of Copper] promotes the reaction [[TYR protein results in increased oxidation of Levodopa] which results in increased chemical synthesis of Melanins]; [CLDN3 protein results in increased expression of SLC31A1 protein] which results in increased import of and results in increased abundance of Copper; [NSC 689534 binds to Copper] which results in decreased expression of CLDN3 mRNA | PMID:20971185 PMID:23053666 | CLDN3 | increases expression | ISO | Cldn3 (Rattus norvegicus) | 6480464 | CTD | Copper results in increased expression of CLDN3 mRNA | PMID:30556269 | CLDN3 | multiple interactions | ISO | Cldn3 (Mus musculus) | 6480464 | CTD | [ATP7A gene mutant form results in increased abundance of Copper] which results in decreased expression of CLDN3 mRNA | PMID:15467011 | | ||||||||||||||||||||||
| Go Back to source page | Continue to Ontology report |