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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 68622
Species: Mus musculus
RGD Object: Gene
Symbol: Pfkm
Name: phosphofructokinase, muscle
Acc ID: CHEBI:27881
Term: resveratrol
Definition: A stilbenol that is stilbene in which the phenyl groups are substituted at positions 3, 5, and 4' by hydroxy groups.
Chemical ID: MESH:C059514
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Pfkmdecreases activityISOPFKM (Homo sapiens)6480464CTDresveratrol results in decreased activity of PFKM proteinPMID:23454376
Pfkmmultiple interactionsISOPFKM (Homo sapiens)6480464CTDAdenosine Diphosphate inhibits the reaction [resveratrol results in decreased activity of PFKM protein]; Adenosine Triphosphate promotes the reaction [resveratrol results in decreased activity of PFKM protein]; Citric Acid promotes the reaction [resveratrol results in decreased activity of PFKM protein]; fructose 2,6-diphosphate inhibits the reaction [resveratrol results in decreased activity of PFKM protein]PMID:23454376
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