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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 68570
Species: Homo sapiens
RGD Object: Gene
Symbol: PDE7A
Name: phosphodiesterase 7A
Acc ID: CHEBI:17489
Term: 3',5'-cyclic AMP
Definition: A 3',5'-cyclic purine nucleotide having having adenine as the nucleobase.
Chemical ID: MESH:D000242
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
PDE7Aincreases hydrolysisEXP 6480464CTDPDE7A protein results in increased hydrolysis of Cyclic AMPPMID:10618442 PMID:10814504
PDE7Amultiple interactionsEXP 6480464CTD1-Methyl-3-isobutylxanthine inhibits the reaction [PDE7A protein results in increased hydrolysis of Cyclic AMP]; Dipyridamole inhibits the reaction [PDE7A protein results in increased hydrolysis of Cyclic AMP]; Papaverine inhibits the reaction [PDE7A protein results in increased hydrolysis of Cyclic AMP]; SCH 51866 inhibits the reaction [PDE7A protein results in increased hydrolysis of Cyclic AMP]PMID:10618442
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