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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 68557
Species: Mus musculus
RGD Object: Gene
Symbol: Ccnd1
Name: cyclin D1
Acc ID: CHEBI:63933
Term: Aroclor 1254
Definition: A mixture of polychlorobiphenyls of unspecified composition, containing 54% chlorine (X = Cl or H).
Chemical ID: MESH:D020111
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ccnd1decreases expressionEXP 6480464CTDChlorodiphenyl (54% Chlorine) results in decreased expression of CCND1 proteinPMID:24216299
Ccnd1multiple interactionsEXP 6480464CTD2,3-bis(4-hydroxyphenyl)-propionitrile promotes the reaction [Chlorodiphenyl (54% Chlorine) results in decreased expression of CCND1 protein]; 4,4',4''-(4-propyl-((1)H)-pyrazole-1,3,5-triyl) tris-phenol inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in decreased expression of CCND1 protein]PMID:24216299
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