GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Ccnd1 | increases expression | EXP | | 6480464 | CTD | arsenite results in increased expression of CCND1 mRNA; arsenite results in increased expression of CCND1 protein | PMID:18191166 PMID:19059425 | Ccnd1 | multiple interactions | EXP | | 6480464 | CTD | JUN mutant form inhibits the reaction [arsenite results in increased expression of CCND1 mRNA] | PMID:19059425 | Ccnd1 | increases expression | ISO | CCND1 (Homo sapiens) | 6480464 | CTD | arsenite results in increased expression of CCND1 mRNA; arsenite results in increased expression of CCND1 protein | PMID:18197291 PMID:19059425 PMID:21040761 PMID:28444938 PMID:31646340 PMID:31773452 | Ccnd1 | multiple interactions | ISO | CCND1 (Homo sapiens) | 6480464 | CTD | [[sodium arsenite results in increased abundance of arsenite] which co-treated with HBEGF protein] results in increased expression of CCND1 mRNA; [[sodium arsenite results in increased abundance of arsenite] which co-treated with HBEGF protein] results in increased expression of CCND1 protein; arsenite inhibits the reaction [Fulvestrant results in decreased expression of CCND1 mRNA]; Decitabine inhibits the reaction [arsenite results in increased expression of CCND1 protein]; EGFR affects the reaction [arsenite results in increased expression of CCND1 protein]; ERBB2 affects the reaction [arsenite results in increased expression of CCND1 protein]; U 0126 inhibits the reaction [arsenite results in increased expression of CCND1 protein] | PMID:21040761 PMID:31616959 PMID:31646340 PMID:31773452 | | ||||||||||||||||||||||
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