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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 68556
Species: Homo sapiens
RGD Object: Gene
Symbol: CCND1
Name: cyclin D1
Acc ID: CHEBI:41922
Term: diethylstilbestrol
Definition: An olefinic compound that is trans-hex-3-ene in which the hydrogens at positions 3 and 4 have been replaced by p-hydroxyphenyl groups.
Chemical ID: MESH:D004054
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CCND1increases expressionEXP 6480464CTDDiethylstilbestrol results in increased expression of CCND1 mRNA; Diethylstilbestrol results in increased expression of CCND1 proteinPMID:22113133 PMID:26865669
CCND1decreases expressionISOCcnd1 (Mus musculus)6480464CTDDiethylstilbestrol results in decreased expression of CCND1 mRNAPMID:15171707 PMID:15591538 PMID:17394237
CCND1increases expressionISOCcnd1 (Rattus norvegicus)6480464CTDDiethylstilbestrol results in increased expression of CCND1 mRNAPMID:15890375
CCND1increases expressionISOCcnd1 (Mus musculus)6480464CTDDiethylstilbestrol results in increased expression of CCND1 mRNAPMID:21041162
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